Tamoxifen is a selective estrogen receptor modulator (SERM) used to treat all stages of hormone receptor-positive breast cancer in women and men. After surgery, it is used to lower the risk that hormone receptor-positive, early-stage breast cancer will return (recur) in women or men. It is also used to treat late-stage, hormone receptor-positive breast cancer in women or men.
Another use is postoperatively to lower the risk of invasive breast cancer for women diagnosed with hormone receptor-positive DCIS (ductal carcinoma in situ). It may be used to lower the risk of breast cancer in women who are at higher-than-average risk for disease and have not been diagnosed.
It is important to know that Tamoxifen shouldn’t be taken at the same time as Arimidex, an aromatase inhibitor, or Femara. Tamoxifen blocks estrogens effects on hormone-receptor-positive breast tumor cells by sitting on top of the cells estrogen receptors. If Tamoxifen is sitting in the receptors, estrogen cannot latch onto the tumor cells, and the cells do not get the estrogen signals to grow and reproduce.
Tamoxifen won’t work on hormone-receptor-negative breast cancer. Tamoxifen has been used to treat hormone receptor-positive breast cancer in millions of women and men. Although an aromatase inhibitor is typically the first hormonal treatment of choice for women after menopause, tamoxifen is a top choice for women before menopause, and it is still a good option for women after menopause who cannot use aromatase inhibitors. Tamoxifen offers other health benefits not related to treating cancer.
Because it is a SERM, it selectively blocks or activates the estrogens effects in certain cells. While Tamoxifen blocks estrogens action in breast cells, it also activates estrogens action in bone and liver cells.
Does Turkey Tail Mushroom Interact with Tamoxifen?
Yes, Turkey tail mushroom may interact negatively with Tamoxifen and can change the way that your body processes Tamoxifen and influence how effective it is.
You should always consult your doctor whenever you are already taking medications and considering adding new supplements into your diet.