Best Reishi Mushroom Supplement of 2023

If you’re looking for an all-natural way to improve your health, you may want to consider taking one of the best reishi mushroom supplements.

Real Mushrooms Reishi Mushroom CapsulesFreshCap Reishi Mushroom CapsulesDouble Wood Supplements
real mushrooms reishi bottle freshcap reishi bottle doube wood reishi bottle
90 capsules
2 per serving (1,000mg)
45 servings
120 capsules
2 per serving (1,000mg)
60 servings
300 capsules
2 per serving (1,000mg)
150 servings
OrganicOrganicNot Organic
Beta Glucan levels >15%Beta Glucan levels 27%Beta Glucan levels unknown
Triterpenoid levels >4%Triterpenoid levels 1.4%Triterpenoid levels unknown
10% discount with code: HealthbyMushrooms10% discount with code "HEALTH10"
image with check price image with check price image with check price

This post contains affiliate links and I will be compensated if you make a purchase after clicking on my links. We and the vendors we highlight appreciate your support.

Reishi mushrooms are known for their many benefits, including reducing inflammation, boosting the immune system, and fighting cancer. They have been used medicinally in Asia for centuries, and more and more people are beginning to take advantage of their health-promoting properties. In this article, we’ll discuss the best reishi mushroom supplements on the market and how they can benefit you.

I spent more than 50 hours investigating (who does that) to figure out which reishi mushroom supplement meets rigorous criteria of quality, honesty, and purity (I just picked up the #1 pick for myself).

By reading below, you will learn:

  1. The 4 most effective reishi mushroom supplements (and why they’re so good)
  2. The history of reishi mushrooms (I’m quite interested in the medicinal history of these mushrooms)
  3. What does the science say about reishi mushrooms (and are they safe?)

If you’re crazy busy, have children to look after while working 3 jobs, or just don’t feel like reading the in-depth review below, here’s a short summary of the finest reishi supplements.

If you’re searching for a great Reishi mushroom supplement, Real Mushrooms’ is the one I suggest. I take it myself, and I’m really satisfied.

One of the reasons why is because of a website I use called Consumer Lab as a resource when purchasing supplements. There are several issues with supplements since they are not regulated, which can cause for some products to not contain what they say they contain.

Fortunately, Consumer Lab independently investigates and analyzes supplements before ranking them. It’s a premium membership I’ve had for years, and it is well worth the money.

Why am I bringing it up? named Real Mushrooms the best reishi mushroom supplement in 2023 after conducting an extensive test. This is exactly what was written by Consumer Lab:

“Real Mushrooms Reishi Extract provided the highest amount of 1,3-beta-D-glucan per serving while also minimizing alpha-glucan (the polysaccharide from grain).”

Beta-glucans are thought to improve the immune system and anti-tumor activity, according on studies. Reishi mushrooms, in their unprocessed form, are high in beta-glucans, which is one of the reasons they’re so beneficial to our health.

What does Consumer Lab have to say about it? Real Mushroom reishi has the most beta glucans of any other reishi supplement on the market, according to Consumer Lab.

Another one of my favorites is Real Mushrooms, which contains a high amount of triterpenes, such as ganoderic acid. Although the research is still in its infancy, it appears to have anti-diabetic, antioxidant, and anti-inflammatory effects.

According to, Real Mushrooms has a high amount of ganoderic acid, however not as much as the Om product (find it in our list below or the table above!).

Is there a disadvantage to this one? Is it possible that there are any drawbacks? The only one I can think of is the cost. It’s more expensive than other choices on the list, but you get what you pay for. It’s the highest quality reishi supplement available-and in my opinion, well worth the investment.

Real Mushrooms Organic Reishi Mushroom Capsules

A great choice for those looking for an organic and gluten-free mushroom supplement. They are made with certified organic reishi mushrooms and contain no fillers or additives. In addition, they are vegan-friendly and have a shelf life of 18 months.


  • Made with 100% organic reishi mushrooms
  • Dual extracted
  • 500mg capsules
  • No grain fillers


  • Does not have mycelium in the extract


  • Reishi Extract 415 1000mg (2 capsules, 45 servings per bottle)
  • >15% beta glucans
  • >4% triterpenoids

image with check price

FreshCap Reishi Capsules

FreshCap’s product is dual extracted and tested for verified levels and the active compounds. Being 100% pure Reishi made from the whole mushroom fruiting body and cracked spore powder, it’s one of the best reishi mushroom supplements on the market.


  • Organic extract
  • Contains beta glucans and triterpene


  • On the pricier side(you get what you pay for)

image with check price


This is without a doubt the greatest Reishi mushroom supplement available. It’s as pure as it gets, free of grain and binders, and includes verified high amounts of immune-boosting beta-glucans and triterpenes. I take this one every morning to get me started. I also recommend it to everyone who asks.

Double Wood Supplements Reishi Mushroom Extract

Another excellent example of a product manufactured from both the fruiting body and Mycelium is Reishi Mushroom extract from Double Wood. This isn’t always a negative thing, as long as the fruiting body is present and most people have been happy with the product. It may help boost your immune function, decrease tiredness, and is supposed to be an antioxidant.


  • Quality is lab tested
  • GMP compliant
  • Non-GMO


  • Anti-oxidant claims may not be supported


  • 4:1 Reishi Mushroom Extract 1,000mg (2 capsules, 150 servings per container)
  • Entire fruiting body and mycelium

image with check price


What’s the research look like for the best reishi mushroom supplements?

Reishi mushrooms have a long history of traditional usage for a range of health issues dating back thousands of years. Human research thus far appears to be beneficial in terms of promoting the immune system, increasing activation, and supporting. Improved quality of life has been demonstrated in cancer patients, although the impact on survival rates and time in cancer have yet to be determined.

Emerging research also shows promise for various effects such as improved cardiac health, anti-inflammatory effects, and support for healthy blood sugar levels.

However, both animal and clinical research have shown promise for a number of reishi mushroom’s typical applications, but additional human study is needed before conclusions may be drawn.

History of Reishi Mushrooms

Reishi mushrooms were so rare and valuable in ancient China that they were only accessible to members of the Chinese aristocracy.

Unlike other medicinal mushrooms eaten for both culinary and medical purposes, reishi mushroom powder is primarily used for their therapeutic effects.

While more study is needed, current findings are fascinating and promising – and I can’t urge you enough to integrate it into your daily diet.

Reishi mushrooms have been used in traditional Chinese medicine for a variety of purposes, including increasing longevity, boosting strength/energy levels, enhancing memory/ cognitive properties, anti-aging effects, treatment of hypertension, liver disease, and cancer.

However, while conventional usage is beneficial, it must be supported by contemporary scientific research. Fortunately, recent study has revealed the active chemical components of reishi mushrooms and the mechanisms through which they work.

What Exactly Does the Research Say About Reishi Mushrooms?

According to researchers, reishi mushrooms have the following anti-cancer characteristics:

  • Toxicity against cancer cells causes them to die.
  • Carcinogens are neutralized.
  • Cancer cell replication and metastasis capabilities for breast, colon, and prostate cancers are disrupted by interference with cancer cell replication and metastasis capabilities
  • Anti-tumor effects against 20 types of human and rodent malignancies, including arrest and apoptosis in cancer cell lines, resulting in cancer cell line death.
  • For mice with a range of cancers, enhanced survival rates and reduced cancer cell and tumor counts were observed.
  • Inhibited angiogenesis (angiogenesis means blood vessel growth, and it’s induced by tumors to promote tumor growth)
  • Study participants with advanced cancer in human randomized controlled trials who received either ZNS or MSCs had enhanced immune system health indicators including improved CD4/CD8 ratios, increased natural killer cell and T-cell counts, and boosted innate immune activity, as well as elevations in IL-2, IL-6, and interferon-y

Reishi mushrooms are known for their ability to boost the immune system and support an active lifestyle. In animal studies, human clinical trials, and pharmacological research, reishi mushroom benefits were shown to be the following:

  • Antioxidant properties
  • Liver protection
  • lowers blood sugar
  • Anti-inflammatory
  • Anti-allergic qualities
  • Antibacterial and anti-viral
  • Cardio protective effects by reducing cholesterol production and reducing platelet adhesion/ clotting

The good news is that reishi mushrooms may now be cultivated in such a way that everyone can enjoy them! However, it’s critical to choose where to buy reishi mushrooms from a place that meets quality standards.

Fortunately, every one of the best mushroom supplements on our list is of exceptional quality.

Are Reishi Mushroom Supplements Safe?

The prestigious Cochrane Library conducted a meta-analysis of 5 randomized controlled trials with a total of 373 participants. The reishi mushrooms were found to be well tolerated, with no safety or harmful effects concerns. Nausea and sleeplessness were reported in one study, along with no serious concerns.

Although reishi mushrooms are available in some countries, the Memorial Sloan Kettering Cancer Center cautions that there are two case reports in the medical literature of liver damage linked to them, one of which resulted in a death. These news are uncommon, although they are important because of their severity given the wide use of reishi mushrooms throughout the world.

If you have an underlying medical condition or are taking prescription drugs, it is important that you talk to your doctor about any potential interactions and side effects of the best mushroom supplements.

Long-term effects in humans are unknown at this time, and research is limited. It’s possible that the best reishi mushroom supplements interact with anticoagulant medications (blood thinners), blood pressure medicines, or diabetic treatments.

Our Final Thoughts on the Best Reishi Mushroom Supplements

Reishi mushrooms are a promising fungus that may help the immune system, anti-cancer effects, antioxidant capabilities, and potentially cardiac health. Despite this, reishi mushrooms are still considered to be a dietary supplement in the United States. However, there is some promising research on their effects.

If you want to include the best reishi mushroom supplements into your health and fitness program, the companies listed above have low-cost, high-quality alternatives! Some even offer reishi mushroom tinctures, which are another great way to get the benefits of this fantastic fungi.

Additional Resources:

The Best Lion’s Mane Supplements

Best Turkey Tail Mushroom Supplements

Where Are Reishi Mushrooms Grown?

How Do You Grow Reishi Mushrooms on Logs?

What Kind of Trees Do Reishi Mushrooms Grow On?

Are Reishi and Shitake Mushrooms the Same?

Updated 1/10/2023

Bruce Wilson

Bruce Wilson

I've studied Mycology and Forest Pathology and love creating content to help other learn more about my passion. Follow along as I continue to explore the amazing world of functional fungi!

Related Posts

Next Post