Best Mushroom Complex of 2023

Mushroom Complex: The Benefits of Combining Powerful Fungi featured image

What is a Mushroom Complex?

Mushroom complex supplements were created to help you get all the amazing benefits of the different mushrooms available on the market in one easy product. Saving you time and money versus needing to buy 5-6 different mushroom supplements, you can just buy one of the mushroom complex supplements we recommend below and get the best bang for your buck.

A mushroom complex has the best 5-6 mushroom species that each have their own unique health benefits. Some of the most popular mushroom species found in mushroom complex supplements include reishi, cordyceps, chaga, lion’s mane, and turkey tail.

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List of the Best Mushroom Complex

Real Mushrooms 5 Defenders Organic Mushroom Complex

realmushrooms 5 defenders mushroom complex supplement bottle image

Coming in capsule form, and also available in a bulk powder, the 5 defenders formula includes an organic blend of reishi, shiitake, maitake, turkey tail, and chaga mushrooms.

Making it a potent mushroom complex offering all the benefits of some of our favorite mushrooms. You can also find it in pure powder form allowing you to add it to your coffee, smoothie, or favorite drink.

  • Made from organic mushrooms
  • Gluten-free, non-gmo, Vegan
  • >20% Beta-glucans
  • No added starch, mycelium, or grain of any kind
  • 500mg capsules, 45 and 100 serving options available
  • quality is verified by 3rd party labs

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FreshCap Ultimate Mushroom Complex

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Another one of our favorites is the FreshCap Ultimate Mushroom Complex (previously called their Thrive 6 complex). We had to mention FreshCap’s blend because it has 6 mushrooms, which is generally more than any other complex out there. Especially considering the serving size of each mushroom available.

The great thing about this blend is that it has you covered with immune boosting, cognition boosting, and energy boosting effects, all in one supplement.

The ultimate Mushroom Complex is a high-quality mushroom extract supplement that’s derived entirely from organic whole fruiting bodies and fully extracted for bioactive chemicals. It’s the ideal combination of mushrooms to deliver all of their amazing qualities.

Each bottle contains 120 capsules (60 servings) of pure mushroom extract powder, equally split between the 6 different species. This blend also comes in the pure powder form for easy mixing with your favorite drink.

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Mushroom Complex Benefits

1. Boosts Immunity

The mushrooms in the complex we promote below are rich in beta-glucans. These are the heavy hitting complex carb that provides a lot of the health benefits described, including boosting the immune system. One study showed that consuming beta-glucans from mushrooms daily for four weeks led to a significant increase in the production of white blood cells, which are vital for fighting off infection.

2. Enhances Brain Function

Mushrooms are also a good source of ergothioneine. Ergothioneine is an antioxidant that protects nervce cells from damage. Leading to improved cognitive function over time since it’s helping preserve the cells themselves. Ergothioneine is not found in many foods, but mushrooms are one of the best sources. Lion’s mane mushroom, in particular, has been shown to improve cognitive function in older adults.

3. Reduces Inflammation

With the benefits we’ve discussed so far, the overarching benefits that mushrooms provide is reducing inflammation. There have been studies done that showed consistent intake of mushroom extracts led to decreases in overall inflammation markers.

4. Fights Cancer

Due to their inflammatory benefits and rich-anti-oxidant levels. Mushrooms can help protect cells from damage thus reducing the risk of cancers. There have been numerous studies showing these potential cancer benefits. And Japan even includes mushrooms in their post-chemo cancer treatment protocols.

5. Promotes Heart Health

Last but not least, these amazing fungi can even help promote heart health by lower cholesterol. One study showed that consuming mushroom powder for eight weeks led to a significant decrease in LDL (bad) cholesterol and an increase in HDL (good) cholesterol.

Mushroom complex supplements are an easy way to get the benefits of all the different mushrooms in one convenient pill.


A mushroom complex is a great way to get the health benefits of all the top fungi available on the market today in one product. Instead of buying 5-6 different supplements, you can get them all-in-one with the brands we mentioned above. Whether in capsule form, or as a powder you want to add to your coffee each day.

Either way, it’s worth giving a mushroom complex a shot to experience the health benefits and overall improvement in wellbeing from one of the most natural sources available in the health and wellness space today!

Learn More:

Mushroom Gummy Benefits

About the author

Bruce Wilson

I've studied Mycology and Forest Pathology and love creating content to help other learn more about my passion. Follow along as I continue to explore the amazing world of functional fungi!

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